Schizophrenia Studies

Treatment for Negative Symptoms of Schizophrenia Study

This research study is evaluating an oral investigational drug when it is given to
participants experiencing negative symptoms of schizophrenia. Study doctors want
to compare the effects of the investigational drug to placebo, which is an inactive
substance that looks like the investigational drug.

Participants will be randomly assigned (like the flip of a coin) to receive either the
investigational drug or placebo. Participants have an equal chance of being assigned
to receive either study drug (investigational or placebo).

Participants will take their study drug twice a day for approximately 15 weeks. Total
study participation will last about 23 weeks.

Study participation includes seven visits to the study center and six phone calls from the study staff. At study center visits, the study doctor and study staff will evaluate participants’ health and response to their study drug.

Key Eligibility Criteria:
To pre-qualify for this study, someone you know must:
• Be 18 to 60 years of age
• Have had onset of symptoms of schizophrenia for at least 1 year and been
clinically stable for at least 6 months
• Be taking antipsychotic medication
• Have experienced negative symptoms for at least 6 months
• Have a reliable informant who can answer questions about him or her

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